F = (AUC_oral × Dose_IV) / (AUC_IV × Dose_oral) × 100%. Calculate absolute bioavailability.
Absolute bioavailability assumes linear pharmacokinetics and the same clearance for both routes. Use AUC0-inf in identical units for both routes and doses in the same units.
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Bioavailability Calc is built on published formulas and reference ranges from established health sources. We revisit it periodically as guidance evolves; the "Last reviewed" date above shows when that last happened. If something looks wrong, tell us with the feedback button in the bottom-right corner.
No. Bioavailability Calc gives you a general estimate based on the inputs you provide, not a diagnosis. Existing conditions, medications, and individual history all change what a number actually means for you. Treat this as a starting point for a conversation with a doctor or other qualified health professional, not a substitute for one.